Yes, replacing the hose on an IP380 can be tricky due to limited access to the thru-hull connection. A few solutions others have used include
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Removing the aft cabin panel or accessing through a cockpit locker to gain better reach.
Using a flexible hose or a longer reach hose clamp tool to handle tight spaces.
Detaching the exhaust elbow to make the removal easier.
It can be a tight fit, so patience and possibly a second set of hands are crucial.